[PDF] Successful Strategies for the Discovery of Antiviral Drugs Manoj C. Desai, Nicholas A. Meanwell, David E Thurston, Robin Ganellin, David Fox, Salvatore Guccione, Ana Martinez, David Rotella, Makonen Belema, David Sperandio, Pei-Yong Shi, Robert Jordan, Randall Halcomb, Christopher Roberts, Brian A Johns, Stephen Griffin, Pierre L Beaulieu, John A McCauley, Mike Sofia, Lianhong Xu, Bill Guyer, Michael R Peel

A volume that will be aimed at medicinal chemistry and emerging drug discovery scientists. The book will be organized according to the various strategies deployed for the discovery and optimization of initial lead compounds. It will be broken down into four main sections: phenotypic and biochemical screening, structure and physical property-based drug design and delivery of antiviral agents.? Each chapter will provide an in depth view of the development of leads and drug candidates in specific areas of contemporary antiviral drug discovery, capturing molecules that have been in advanced phases of clinical investigation. The focus of the book will be on capturing tactical aspects of problem solving in antiviral drug design, an approach that will hold special appeal for those engaged in antiviral drug development but will also appeal to the broader chemistry community based on its focus on tactical aspects of drug design.