Content:
Chapter 1 Opening Remarks (pages 1?2):
Chapter 2 Synthesis and Properties of Purines of Potential Biological Interest (pages 3?19): Aaron Bendich, Alfredo Giner?Sorolla and Jack J. Fox
Chapter 3 Some Synthetic Studies on Purines and Related Heterocycles (pages 20?38): E. C. Taylor, T. S. Osdene, E. Richter and O. Vogl
Chapter 4 Some New N?Methylpurines (pages 39?49): Gertrude B. Elion
Chapter 5 The Structure of the Hydroxypurines Investigated by O? and N?Methylation (pages 50?59): D. J. Brown
Chapter 6 The Spectra and Structure of the Monohydroxypurines and Other Potentially Tautomeric Purines (pages 60?71): S. F. Mason
Chapter 7 The ??Electron Properties of Purine Calculated by the L.C.A.O. Method (pages 72?76): S. F. Mason
Chapter 8 The Degradation of Uric Acid by Water Under Pressure (pages 77?96): Wolfgang Pfleiderer
Chapter 9 The 8?Position in Purines. The Chemical and Biological Transformation of Purines Into Pteridines (pages 97?107): Adrien Albert
Chapter 10 Cyclonucleosides (pages 108?119): D. M. Brown, Sir Alexander Todd and S. Varadarajan
Chapter 11 Stereochemistry of Nucleoside Synthesis (pages 120?133): B. R. Baker
Chapter 12 Synthetic Chemical Investigations Related to the Metabolism of Purines (pages 134?145): G. M. Timmis, I. Cooke and R. G. W. Spickett
Chapter 13 The Effects of Potential Antipurines on a Purine?Requiring Strain of Escherichia coli (pages 146?159): H. O. J. Collier and Patricia L. Huskinson
Chapter 14 The Chemistry of New Purines in the B (pages 160?168): E. Lester Smith
Chapter 15 Biological and Microbiological Activity of Purine Analogues of Vitamin B (pages 169?176): S. K. Kon
Chapter 16 Puromycin (pages 177?191): Brian L. Hutchings
Chapter 17 Chemical and Biological Behaviours of 9???d?Ribofuranosylpurine (pages 192?203): G. B. Brown, M. P. Gordon, D. I. Magrath and A. Hampton
Chapter 18 On the Activation of the One?Carbon Unit for the Biosynthesis of Purine Nucleotides (pages 204?232): G. Robert Geeenberg and Lothar Jaenicke
Chapter 19 The Enzymatic Synthesis of Inosinic Acid De Novo (pages 233?255): J. M. Buchanan, J. G. Flaks, S. C. Hartman, B. Levenberg, L. N. Lukens and L. Warren
Chapter 20 Enzymic Control of Purines by Xanthine Oxidase (pages 256?269): F. Bergel, R. C. Bray, A. Haddow and I. Lewin
Chapter 21 The Biological Effects of 8?Azapurines (pages 270?285): R. E. F. Matthews
Chapter 22 Biochemical Effects of 6?Mercaptopurine (pages 286?308): Gertrude B. Elion and George H. Hitchings
Chapter 23 The Use of 6?Mercaptopurine in the Treatment of Leukaemia (pages 299?307): D. A. G. Galton
Chapter 23 General Discussion (pages 308?317):
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