[PDF] Combinatorial chemistry : from theory to application Willi Bannwarth; Berthold Hinzen; John Wiley & Sons

The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new chapter on screening complements the overview of combinatorial strategy and synthetic methods. “Experimental details and complete reaction data … are a constant theme running through this work”. (Angewandte Chemie). “Recommended to newcomers in the field of combinatorial chemical synthesis because of its broad scope”. (Journal of the American Chemical Society). ?Read more… Purification principles in high-speed solution-phase synthesis / Steffen Weinbrenner, C. Christoph Tzschucke — Linkers for solid-phase organic synthesis (SPOS) and combinatorial approaches on solid supports / Willi Bannwarth — Cyclative cleavage : a versatile concept in solid-phase organic chemistry / Josef Pernerstorfer — C-C bond-forming reactions / Wolfgang K.-D. Brill, Gianluca Papeo — Combinatorial synthesis of heterocycles / Eduard R. Felder, Andreas L. Marzinzik — Polymer-supported reagents : preparation and use in parallel organic synthesis / Berthold Hinzen, Michael G. Hahn — Encoding strategies for combinatorial libraries / Berthold Hinzen — Automation and devices for combinatorial chemistry and parallel organic synthesis / Christian Zechel — Computer-assisted library design / Andreas Dominik — Assays for high-throughput screening in drug discovery / Christian M. Apfel, Thilo Enderle