[PDF] New applications of nmr in drug discovery and development

Content: Introduction; Part I. Small Molecules, Proteins, Cellular Systems: New Applications of High; Resolution NMR in Drug Discovery and Development; Solid-state NMR in Drug Discovery and Development; Part II. The Whole Organism in Vivo: Increased Sensitivity Using Cryogenic; Radiofrequency Coils: Application to In Vivo Phenotyping of Mice; Recent Developments of Contrast Agents, CEST and Low Fields; Pharmacological fMRI in Drug Discovery and Development; Part III. Translational drug discovery: From Biological Models to the Clinics; Translational Magnetic Resonance Imaging and Spectroscopy: Opportunities and Challenges